Cerebellum Sub-Segmentation (CerebNet)

The cerebellum module (cereb): a deep learning network (CerebNet) that divides the cerebellum into its lobules and separates gray and white matter, and computes volume statistics for them.

What it computes

  • A sub-segmentation of the cerebellum with a detailed delineation of gray and white matter (cerebellum.CerebNet.nii.gz).

  • Volume statistics for the cerebellar structures, corrected for partial volume effects (cerebellum.CerebNet.stats).

The output files are listed in the output files overview.

What it needs

  • A T1-weighted image, see the requirements to input images.

  • The whole-brain segmentation of the FastSurferVINN module, which locates the cerebellum.

  • CerebNet works at 1 mm: images with smaller voxels are resampled to 1 mm for it, and its outputs are at 1 mm.

The module adds a few minutes on a GPU to the segmentation.

Options

The module runs by default, as part of the segmentation. The options of run_fastsurfer.sh for it:

  • --no_cereb: skip this module.

  • --cereb_segfile <path>: where to write the segmentation (default mri/cerebellum.CerebNet.nii.gz).

  • --no_biasfield: skip the partial-volume corrected statistics.

All options are described in the run_fastsurfer.sh reference. To run the network script directly, see CerebNet in the command reference.

References

If you use the cerebellum sub-segmentation in your research, please cite:

  • Faber J*, Kuegler D*, Bahrami E*, et al. (*co-first) CerebNet: A fast and reliable deep-learning pipeline for detailed cerebellum sub-segmentation. NeuroImage 264 (2022), 119703. doi:10.1016/j.neuroimage.2022.119703