We develop open, validated computational tools at the intersection of deep learning, medical image computing, and computational geometry.
Fast, accurate, deep-learning pipeline for whole-brain segmentation in under a minute and full surface reconstruction in about an hour. Produces FreeSurfer-conform outputs for large-cohort and clinical use.
GPU-accelerated Python toolkit for neuroimaging registration — same-modality, cross-modal, boundary-based, and multi-timepoint — plus transform and volume utilities. Replaces FreeSurfer's mri_robust_register, mri_coreg, and bbregister. Usable from the command line or as a library.
Automated geometry-based method for hippocampal shape and thickness analysis from structural MRI, enabling fine-grained morphometric studies of the hippocampus.
AI-powered neuroimaging platform combining an MRI viewer with integrated pipelines like FastSurfer. Run complex structural imaging workflows through a GUI or conversational AI — no command line required.
Automated adipose tissue segmentation and field-of-view estimation in whole-body Dixon MRI, enabling large-scale body composition studies.
Shape and asymmetry analysis of neuroanatomical structures using Laplace-Beltrami spectral descriptors for group studies and individual subject classification.
Cortical surface parcellation using projection-based 3D convolutional neural networks operating on spherical mesh representations.
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Python library for geometric mesh processing and finite element method (FEM) differential geometry computations on triangular and tetrahedral meshes.
Python/OpenGL tool for rendering surface meshes with color overlays and generating publication-quality screenshots — fully offscreen (no GPU required), runs in Docker and headless environments, as well as from the command line, Jupyter notebooks, or an interactive desktop GUI.
Automated quality check tools for surface-based morphometry outputs from FastSurfer and FreeSurfer, enabling quality control at scale.
All code is open source and available on github.com/Deep-MI.
Our work spans computational neuroimaging, geometric deep learning, and medical image analysis. In close collaboration with clinical and industrial partners, we develop next-generation methods for large-scale biomedical imaging datasets.
Deep-learning methods for reliable image segmentation, registration, and reconstruction — with a focus on sensitivity in longitudinal studies and generalizability across scanners and protocols.
Statistical modeling and computer vision for extracting clinically relevant biomarkers from large datasets — supporting computer-aided diagnosis, prognosis, and personalized medicine.
Differential and computational geometry methods for shape analysis, spectral descriptors, and surface-based morphometry of neuroanatomical structures.
Understanding brain development and neurodegeneration (aging, Alzheimer's, Huntington's disease) via multi-modal imaging of large population cohorts such as the Rhineland Study.
All research from the Deep-MI lab is backed by peer-reviewed publications. You can find the full list on the publications page or on Google Scholar.