Deep-MI Lab
← Deep-MI Lab

Research & Projects

We develop open, validated computational tools at the intersection of deep learning, medical image computing, and computational geometry.

FastSurfer
Neuroimaging Pipeline
FastSurfer

Fast, accurate, deep-learning pipeline for whole-brain segmentation in under a minute and full surface reconstruction in about an hour. Produces FreeSurfer-conform outputs for large-cohort and clinical use.

deep-mi/FastSurfer
NeuroReg
Image Registration
NeuroReg

GPU-accelerated Python toolkit for neuroimaging registration — same-modality, cross-modal, boundary-based, and multi-timepoint — plus transform and volume utilities. Replaces FreeSurfer's mri_robust_register, mri_coreg, and bbregister. Usable from the command line or as a library.

deep-mi/neuroreg
HipSTA
Shape Analysis
HipSTA

Automated geometry-based method for hippocampal shape and thickness analysis from structural MRI, enabling fine-grained morphometric studies of the hippocampus.

deep-mi/hipsta
NeuroCade
Neuroimaging Platform
NeuroCade

AI-powered neuroimaging platform combining an MRI viewer with integrated pipelines like FastSurfer. Run complex structural imaging workflows through a GUI or conversational AI — no command line required.

deep-mi/NeuroCade
FatSegNet
MRI Segmentation
FatSegNet

Automated adipose tissue segmentation and field-of-view estimation in whole-body Dixon MRI, enabling large-scale body composition studies.

deep-mi/FatSegNet
BrainPrint
Shape Analysis
BrainPrint

Shape and asymmetry analysis of neuroanatomical structures using Laplace-Beltrami spectral descriptors for group studies and individual subject classification.

Deep-MI/BrainPrint
p3CNN
Cortical Surface
p3CNN

Cortical surface parcellation using projection-based 3D convolutional neural networks operating on spherical mesh representations.

Learn more →
LaPy
Python Library
LaPy

Python library for geometric mesh processing and finite element method (FEM) differential geometry computations on triangular and tetrahedral meshes.

deep-mi/LaPy
WhipperSnapPy
Visualization
WhipperSnapPy

Python/OpenGL tool for rendering surface meshes with color overlays and generating publication-quality screenshots — fully offscreen (no GPU required), runs in Docker and headless environments, as well as from the command line, Jupyter notebooks, or an interactive desktop GUI.

deep-mi/WhipperSnapPy
FastSurfer QC
Quality Control
FastSurfer QC

Automated quality check tools for surface-based morphometry outputs from FastSurfer and FreeSurfer, enabling quality control at scale.

deep-mi/qatools-python

All code is open source and available on github.com/Deep-MI.

Research Directions

Our work spans computational neuroimaging, geometric deep learning, and medical image analysis. In close collaboration with clinical and industrial partners, we develop next-generation methods for large-scale biomedical imaging datasets.

Medical Image Segmentation & Analysis

Deep-learning methods for reliable image segmentation, registration, and reconstruction — with a focus on sensitivity in longitudinal studies and generalizability across scanners and protocols.

Biomarker Extraction & Clinical Translation

Statistical modeling and computer vision for extracting clinically relevant biomarkers from large datasets — supporting computer-aided diagnosis, prognosis, and personalized medicine.

Computational Geometry & Topology

Differential and computational geometry methods for shape analysis, spectral descriptors, and surface-based morphometry of neuroanatomical structures.

Neurodegeneration & Brain Development

Understanding brain development and neurodegeneration (aging, Alzheimer's, Huntington's disease) via multi-modal imaging of large population cohorts such as the Rhineland Study.

Publications

All research from the Deep-MI lab is backed by peer-reviewed publications. You can find the full list on the publications page or on Google Scholar.

View all publications → Google Scholar →