Deep-learning neuroimaging pipeline

Brain MRI analysis in minutes, not hours.

FastSurfer is a fast, accurate, and extensively validated pipeline for fully automated processing of structural human brain MRI — with FreeSurfer-conform outputs.

Whole-brain segmentation in under a minute · full surface reconstruction in about an hour · free & open source.

FastSurfer processing pipeline overview

Why FastSurfer?

Everything you expect from a full surface-based morphometry pipeline — at a fraction of the runtime.

Fast

Whole-brain segmentation in under a minute on a GPU; the full surface pipeline in about an hour — instead of many hours.

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Accurate & validated

Extensively validated for accuracy, generalizability, reliability and sensitivity across many public datasets.

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FreeSurfer-conform

Produces outputs compatible with FreeSurfer, so it drops into your existing analysis workflows.

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Scalable & open

Built for big-data cohorts and time-critical clinical use. Free and open source, with an active community.

Get up and running quickly

Run the segmentation pipeline on a single T1-weighted scan. Choose the option that fits your setup: Apptainer for HPC clusters, Docker for workstations and servers, or the native package for macOS. See the documentation for GPU setup and all options.

Full documentation →
# Pull once — saves a portable .sif file
$ apptainer pull fastsurfer.sif \
    docker://deepmi/fastsurfer:latest

# Run segmentation (--nv enables GPU, -B binds data dir)
$ apptainer run --nv -B /data:/data fastsurfer.sif \
    --t1 /data/subject/orig.mgz \
    --sid subjectID --sd /data/output --seg_only

On macOS? Use the native package installer — see the installation guide →

One pipeline, whole-brain output

FastSurfer combines an advanced neural-network segmentation (FastSurferCNN / VINN) with a fast surface pipeline (recon-surf) for volumes, cortical surfaces, thickness and parcellations.

FastSurfer outputs: whole-brain segmentation, cortical surfaces and sub-segmentations
FastSurfer's fully automated pipeline — from raw T1 to segmentation, surfaces and detailed sub-structures.
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See it for yourself — right now

Explore a real FastSurfer whole-brain segmentation interactively in your browser with NeuroCade. No installation, no account required.

Open in NeuroCade ↗

Web-based viewer · full-brain segmentation · runs in any modern browser

The science behind FastSurfer

FastSurfer and its modules are backed by peer-reviewed publications. Using FastSurfer in your work? Please cite the relevant papers.

Ready to try FastSurfer?

Get up and running with the documentation, or explore the source on GitHub.